Clinical evaluation of 67Ga scanning in the diagnosis of anaplastic carcinoma and malignant lymphoma of the thyroid.

Abstract
Whereas 67Ga uptake has been reported to be highly variable and nonspecific in the diagnosis of malignant tumors of the [human] thyroid, it has also been observed to depend on the histological nature of the lesion. For this reason, the behavior of 67Ga in various types of thyroid cancer was investigated in a prospective study of 86 patients with thyroid masses compatible with anaplastic carcinoma or malignant lymphoma. A distinct difference in uptake was demonstrated between well-differentiated adenocarcinoma of the thyroid and the more undifferentiated anaplastic carcinoma and malignant lymphoma.