Linkage analysis of Alzheimer disease with psychosis
- 9 July 2002
- journal article
- Published by Wolters Kluwer Health in Neurology
- Vol. 59 (1) , 118-120
- https://doi.org/10.1212/wnl.59.1.118
Abstract
Although a portion of risk for late-onset AD (LOAD) is attributable to APOE, the search for other loci is ongoing. The authors hypothesize that psychotic symptoms with LOAD (LOAD+P) identify a potentially more etiologically homogeneous form of AD. Linkage analysis of families with LOAD+P identified one significant and several suggestive novel linkage signals, which bolsters the conjecture of greater etiologic homogeneity.Keywords
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