A Marvellous Machine for Making Messages
- 8 June 2001
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 292 (5523) , 1844-1846
- https://doi.org/10.1126/science.1062384
Abstract
The wonderful x-ray structures of RNA polymerase published in the past 3 years have revealed a wealth of information about how genes are transcribed. In an eloquent Perspective, Klug describes the latest tour de force from Kornberg9s laboratory: the crystal structure of yeast RNA polymerase II in action.Keywords
This publication has 20 references indexed in Scilit:
- Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å ResolutionScience, 2001
- Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom ResolutionScience, 2001
- Architecture of RNA Polymerase II and Implications for the Transcription MechanismScience, 2000
- Electron Crystal Structure of an RNA Polymerase II Transcription Elongation ComplexCell, 1999
- Yeast RNA Polymerase II at 5 Å ResolutionCell, 1999
- Crystal Structure of Thermus aquaticus Core RNA Polymerase at 3.3 Å ResolutionCell, 1999
- Formation and Crystallization of Yeast RNA Polymerase II Elongation ComplexesPublished by Elsevier ,1997
- Accurate initiation at RNA polymerase II promoters in extracts from Saccharomyces cerevisiae.Proceedings of the National Academy of Sciences, 1987
- Two-dimensional crystallization technique for imaging macromolecules, with application to antigen–antibody–complement complexesNature, 1983
- Selective and accurate initiation of transcription at the ad2 major late promotor in a soluble system dependent on purified rna polymerase ii and dnaCell, 1979