Studies on the half life time of rat liver transfer RNA species
- 18 November 1970
- journal article
- Published by Wiley in FEBS Letters
- Vol. 11 (2) , 78-80
- https://doi.org/10.1016/0014-5793(70)80496-3
Abstract
The tRNA fraction, extracted from very high speed supernatant fluid, from livers of rats injected with 3H‐orotic acid, attained maximum specific activity after a little over 24 hr and, thereafter, decayed with an apparent half life of 5 days. This behaviour of tRNA was indistinguishable from that of liver rRNA and the acid soluble pool. Chromatography of tRNA, doubly labelled during a period of short synthesis and of prolonged decay, on a BD cellulose column, indicated that individual tRNA species turn over at a constant rate with respect to one another.Keywords
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