Canonical formulation of linkage thermodynamics.
- 1 July 1988
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 85 (14) , 5077-5081
- https://doi.org/10.1073/pnas.85.14.5077
Abstract
The canonical structure of the group of thermodynamic potentials obtained from the energy of a physico-chemical system removes any possible distinction between physical and chemical binding phenomena. Transformations of these potentials by means of Jacobians give linkage relations for equilibrium thermodynamics. Linkage matrices are introduced to explore the functional properties of a biological macromolecule. They provide a quantitative basis for a broader approach and understanding of generalized binding phenomena.Keywords
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