Effects of oral administration of dilantin sodium on abnormal behavior in the rat.
- 1 August 1944
- journal article
- research article
- Published by American Psychological Association (APA) in Journal of Comparative Psychology
- Vol. 37 (4) , 243-250
- https://doi.org/10.1037/h0056859
Abstract
"Ten rats of known susceptibility to behavior disturbances on exposure to sound snowed an appreciable decrease in the incidence of attacks when doses of crystalline dilantin ranging from 64 mgm to 79 mgm/100 gr./day were administered orally in conjunction with a dry diet, while doses of 25 mgm/100 gr./day had little if any protective action. The effect may be comparable to the protective action of the drug which has been demonstrated clinically with human epileptic patients, and may be due, at least in part, to depression of certain central nervous functions.".Keywords
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