Functional Cooperation Between Smad Proteins and Activator Protein-1 Regulates Transforming Growth Factor-β–Mediated Induction of Endothelin-1 Expression
- 27 June 2003
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 92 (12) , 1288-1295
- https://doi.org/10.1161/01.res.0000078491.79697.7f
Abstract
Endothelin-1 (ET-1) is a 21–amino-acid potent vasoconstrictor peptide that is mainly produced by vascular endothelial cells. Expression of the ET-1 gene is subject to complex regulation by numerous...Keywords
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