Hyperglycemic Activity in Dogs of Recombinant DNA-Derived 20,000 Dalton Variant of Methionyl Human Growth Hormone
- 1 January 1986
- journal article
- research article
- Published by Taylor & Francis in Endocrine Research
- Vol. 12 (1) , 21-35
- https://doi.org/10.1080/07435808609023651
Abstract
The recombinant DNA-derived 20,000-dalton variant of N-terminal methionyl human growth hormone (20K-Met-hGH) had a hyperglycemic effect in fasted dogs when injected 11 hours prior to an oral glucose tolerance test (OGTT). These results reported here suggest that 20K-Met-hGH can induce glucose intolerance in dogs similar to that produced by recombinant DNA-derived 22,000 dalton N-terminal methionyl human growth hormone (22K-Met-hGH) and the normal pituitary-source human growth hormone (22K-hGH).This publication has 16 references indexed in Scilit:
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