LOCALIZATION OF RADIOACTIVITY AFTER ADMINISTRATION OF LABELED PROLACTIN PREPARATIONS TO THE FEMALE RAT

1 December 1951

journal article
research article
Published by The Endocrine Society in Endocrinology

Vol. 49 (6) , 709-719
https://doi.org/10.1210/endo-49-6-709

Abstract

PREVIOUS reports have indicated that anterior pituitary hormone preparations can be labeled with radioactive isotopes (Sonenberg, Keston and Money, 1950 and 1951). In these earlier studies, hormone preparations with adrenocorticotropic activity were labeled with traces of radioactive iodine, I¹³¹. Preparations labeled in this manner were then used to investigate the localization of radioactivity after being administered to rats. The technique of trace labeling proteins has been extended to other preparations containing pituitary hormones. This report presents the results of studies with prolactin preparations labeled with radioactive iodine.

Keywords

RADIOACTIVITY

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