GROWTH OF FOOT-AND-MOUTH DISEASE VIRUS IN DISPERSED TISSUE CELLS .1. METHODS OF PRODUCTION

  • 1 January 1962
    • journal article
    • research article
    • Vol. 26  (8) , 186-+
Abstract
Foot-and-mouth disease virus grown in stationary cultures of trypsin-dispersed bovine kidney cells yielded between 107 and 108 plaque-forming units/ml. The cells were grown in a lactalbumin hydrolysate medium containing 2% bovine serum and a maintenance medium containing peptone but no serum. The method had the advantages of using less culture medium, eliminating medium changes, less contamination risk and eliminating the need of agitating or gassing the cultures.