A Hybridoma Cell Line Secreting Antibody to Poliovirus Type 3 D-Antigen: Detection in Virus Harvest of Two D-Antigen Populations
- 1 June 1981
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 54 (2) , 437-442
- https://doi.org/10.1099/0022-1317-54-2-437
Abstract
A mouse hybridoma cell line (Mo56) secreting IgG antibody to poliovirus type 3 D-antigen was obtained by fusion of a mouse myeloma cell line with spleen cells from mice immunized with Saukett virus. The monoclonal antibody was specific for Saukett virus strains in virus-neutralization and single-radial-diffusion tests. In immunoprecipitation tests the monoclonal antibody reacted with intact infectious virus particles (155S) and with a previously undescribed 70S poliovirus particle with D-antigenic reactivity.This publication has 5 references indexed in Scilit:
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