Puerperal Hyperuricaemia

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Abstract
Serum uric acid levels of 6 mg % or more were demonstrated in 23 (26%) out of 88 patients with pre-eclamptic toxemia of pregnancy, and hyperuricemia was shown to persist after delivery in 17 cases for 1 week, in 8 for 4 weeks, in 4 for 8 weeks, in 3 for 12 weeks, and in 2 for 16 weeks. One case remained hyperuricemic 6 months post-partum. These results, together with the known decrease in glomerular filtration rate and effective renal plasma flow during pre-eclamptic toxemia, and recent histological studies, suggest that renal cellular damage is responsible for toxemic hyperuricemia and that this damage may persist for a variable period into the puerperium.