Fungitoxicity of essential oils against dermatophytes
- 1 May 1993
- Vol. 36 (5-6) , 211-215
- https://doi.org/10.1111/j.1439-0507.1993.tb00753.x
Abstract
Summary. Sixteen essential oils were screened in vitro for their fungitoxicity against the two dermatophytes Trichophyton rubrum and Microsporum gypseum. Five oils (from Artemisia nela‐grica, Caesulia axillaris, Chenopodium ambrosioides, Cymbopogon citratus and Mentha arvensis) showed strong activity and were assessed for their fungitoxicity against eight other dermatophytes as well as against Aspergillus fumigatus and Cladosporium trichoides. These five essential oils by formulation of ointments were able to cure experimental ringworm in guinea pigs within 7 to 12 days. Artemisia oil was found to be the most effective essential oil.Zusammenfassung. Sechzehn ätherische Öle wurden in vitro auf ihre Fungitoxizität für die zwei Dermatophyten Trichophyton rubrum und Microsporum gypseum untersucht. Fünf Öle (von Artemisia nelagrica, Caesulia axillaris, Chenopodium ambrosioides, Cymbopogon citratus und Mentha arvensis) zeigten hohe Aktivität und wurden auf ihre Fungitoxizität für acht weitere Dermatophyten sowie für Aspergillus fumigatus und Cladosporium trichoides getestet. Diese finf ätherischen Öle waren in Salbenform in der Lage, experimentelle Tinea an Meerschweinchen innerhalb von 7–12 Tagen zu heilen. Artemisia‐ÖI erwies sich als das wirksamste.Keywords
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