Detection of a large T-cell reservoir able to replicate HIV-1 actively in breast milk
- 26 June 2006
- journal article
- Published by Wolters Kluwer Health in AIDS
- Vol. 20 (10) , 1453-1455
- https://doi.org/10.1097/01.aids.0000233581.64467.55
Abstract
In breast milk and paired blood samples of nine HIV-1-infected lactating women, we undertook a study to detect a CD4 T-cell reservoir and to investigate its capacity to enter viral production after activation. Breast milk-infected CD4 T cells have a greater capacity to produce viral particles actively than blood CD4 T cells. This observation may explain the apparent paradox of a transmissible viral infection from a body fluid with a low viral concentration.Keywords
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