THE EFFECT OF LITHIUM PERIODATE ON CRYSTALLINE BOVINE SERUM ALBUMIN
Open Access
- 1 May 1949
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 89 (5) , 479-489
- https://doi.org/10.1084/jem.89.5.479
Abstract
A study of the chemical, physicochemical, and immunological changes in bovine serum albumin, brought about by oxidation with lithium periodate, has been made. It has been shown that destruction of certain amino acids occurs, that a change in the absorption spectrum takes place, and that the electrophoretic behavior of the protein is altered. Prolonged contact of bovine albumin with lithium periodate destroys its ability to incite antibodies in experimental animals.Keywords
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