The action of botulinum A neurotoxin on the inhibition by antidromic stimulation of the lumbar monosynaptic reflex
- 1 July 1977
- journal article
- conference paper
- Published by Springer Nature in Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie
- Vol. 298 (3) , 235-238
- https://doi.org/10.1007/bf00500893
Abstract
1. Botulinum toxin type A was injected into gastrocnemius muscles of cats and 2 days later its action on the monosynaptic gastrocnemius reflex and on the recurrent inhibition was investigated. 2. In early local botulism, no significant change in the monosynaptic gastrocnemius reflex was observed. 3. The inhibition by antidromic stimulation of the monosynaptic gastrocnemius reflex was significantly reduced. 4. During the early phases of local botulism an action of botulinum toxin on parts of the soma membrane of the α-motoneuron is suggested.Keywords
This publication has 11 references indexed in Scilit:
- Binding of botulinum neurotoxin to the synaptosome fraction of rat brainNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1976
- 125I-Labelled botulinum a neurotoxin: Pharmacokinetics in cats after intramuscular injectionNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1976
- Direct evidence for the specific fixation of Cl. Botulinum A neurotoxin to brain matterNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1975
- Proceedings: Type A botulinum toxin in cats: neural ascent and action on spinal cord reflexes.1974
- 125I-labeled neurotoxin from clostridium botulinum A: Preparation, binding to synaptosomes and ascent to the spinal cordNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1974
- The action of tetanus toxin on preganglionic sympathetic reflex dischargesNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1973
- Mechanism of disturbances of electrical activity of spinal cord neurons in experimental botulismBulletin of Experimental Biology and Medicine, 1968
- Distribution of recurrent inhibition among motoneuronesThe Journal of Physiology, 1961
- Electrophysiological analysis of disturbances in reflex activity of the spinal cord in experimental botulism type a in warm — and cold-blooded animalsBulletin of Experimental Biology and Medicine, 1958
- THE DISTRIBUTION OF THE RATIO, IN A SINGLE NORMAL SAMPLE, OF RANGE TO STANDARD DEVIATIONBiometrika, 1954