Statins Cause Intracellular Accumulation of Amyloid Precursor Protein, β-Secretase-cleaved Fragments, and Amyloid β-Peptide via an Isoprenoid-dependent Mechanism

This publication has 71 references indexed in Scilit:

• Evidence That Assembly of an Active γ-Secretase Complex Occurs in the Early Compartments of the Secretory Pathway
  Journal of Biological Chemistry, 2004
• RETRACTED: Statin blocks Rho/Rho-kinase signalling and disrupts the actin cytoskeleton: relationship to enhancement of LPS-mediated nitric oxide synthesis in vascular smooth muscle cells
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2004
• Aβ localization in abnormal endosomes: association with earliest Aβ elevations in AD and Down syndrome
  Neurobiology of Aging, 2004
• Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts
  The Journal of cell biology, 2003
• The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Aβ protofibril formation
  Nature Neuroscience, 2001
• Elevated Low-Density Lipoprotein in Alzheimer's Disease Correlates with Brain Aβ 1–42 Levels
  Biochemical and Biophysical Research Communications, 1998
• Differential Effects of a Rab6 Mutant on Secretory Versus Amyloidogenic Processing of Alzheimer's β-Amyloid Precursor Protein
  Journal of Biological Chemistry, 1996
• Plasma lipids and cholesterol esterification in Alzheimer's disease
  Mechanisms of Ageing and Development, 1994
• Regulation of the mevalonate pathway
  Nature, 1990
• Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
  Biochemical and Biophysical Research Communications, 1984