Emergence in Italy of a Neisseria meningitidis Clone with Decreased Susceptibility to Penicillin
- 1 August 2004
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 48 (8) , 3103-6
- https://doi.org/10.1128/aac.48.8.3103-3106.2004
Abstract
A rise in invasive diseases due to Neisseria meningitidis C:2b:P1.5 with decreased penicillin susceptibility occurred in Italy during the last 2 years. Real-time PCR identified the Peni phenotype, and the penA sequence revealed the mosaicism of the gene. Molecular analyses assigned the isolates to a single emergent clone of the hypervirulent A4 cluster.Keywords
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