Experimental Studies on Human Health Effects of Air Pollutants. IV. Short-Term Physiological and Clinical Effects of Nitrogen Dioxide Exposure
- 1 July 1978
- journal article
- research article
- Published by Taylor & Francis in Archives of environmental health
- Vol. 33 (4) , 176-181
- https://doi.org/10.1080/00039896.1978.10667330
Abstract
Adult male volunteers were exposed to NO2 at 1.0 ppm in purified air under conditions simulating ambient photochemical smog exposures (2 h exposure with intermittent light exercise at 31.degree. C and 35% relative humidity). Sham exposures to purified air alone served as controls. Exposure effects were assessed by pulmonary physiological tests and by a standardized clinical evaluation. No statistically significally physiological changes attributable to NO2 exposure were found except for a marginal loss in forced vital capacity after exposure on 2 successive days (1.5% mean decrease, P < .05). Reported respiratory and other symptoms were slightly increased with exposure as compared to control, but the change was not significant. Short-term toxicity of NO2 at peak ambient concentrations appears to be substantially less than that of ozone in healthy people, but adverse NO2 effects in diseased people or in long-term exposures cannot be ruled out at present.This publication has 6 references indexed in Scilit:
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