Cyclic Metabolites of Etidocaine in Humans
- 1 January 1977
- journal article
- research article
- Published by Taylor & Francis in Xenobiotica
- Vol. 7 (6) , 365-375
- https://doi.org/10.3109/00498257709035795
Abstract
1. Three cyclic metabolites of etidocaine excreted in urine of man have been investigated by g.I.c.-mass spectrometry. 2. These metabolites have been identified as 3-(2,6-dimethylphenyl)-5-ethyl-2,4-imidazolidinedione, 1-(2,6-dimethylphenyl)-2-methyl-4-ethyl-2-imidazolin-5-one and 1-(2,6-dimethylphenyl)-2,4-diethyl-2-imidazolin-5-one. 3. Formation in vivo of two of the metabolites is proposed to proceed via carbinolamine intermediates.This publication has 7 references indexed in Scilit:
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