TRANSIENT FREE RADICAL FORMS OF HORMONES: EPR SPECTRA FROM CATECHOLAMINES AND ADRENOCHROME
- 1 March 1965
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 53 (3) , 633-639
- https://doi.org/10.1073/pnas.53.3.633
Abstract
A high-velocity continuous flow apparatus permitted EPR (electron paramagnetic resonance) spectroscopy of the labile free radicals formed in solution by inorganic redox agents from a number of hormone molecules and their congeners. In this report the existence of hormonal free radicals was confirmed for catechola-mine hormones (epinephrine, norepinephrine) and adrenochrome. A concluding part of this communication will present similar data regarding iodothyronines, indole hormones (serotonin, indole acetic, and butyric acids), estrogens (steroids and nonsteroidal synthetics), and 1 protein hormone (insulin).Keywords
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