Microsatellites in the HLA region: 1998 update

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Abstract
In order to update the review published in Tissue Antigens in 1997, we present here a new overview on microsatellites in the HLA region, including additional information, with focus on the following points: • Description of 103 microsatellite characteristics in the HLA region, 50 markers having been newly described since 1996. • An integrated map of the HLA region, including microsatellites and some HLA genes, revealing an important microsatellite density in the MHC (Class I, Class II and Class HI regions). • A synthesis of microsatellite analysis in disease studies, summarizing results of microsatellite approaches in 24 pathologies, including autoimmune diseases, HLA‐associated or HLA‐linked diseases and cancers. • Other applications of HLA region microsatellites in population or transplantation studies.