Colistin-associated Acute Renal Failure: Revisited
- 1 February 2005
- journal article
- research article
- Published by Southern Medical Association in Southern Medical Journal
- Vol. 98 (2) , 257-258
- https://doi.org/10.1097/01.smj.0000152540.45539.98
Abstract
Sodium colistimethate (colistin) is a parenterally administered polymyxin antibiotic that acts by disrupting bacterial cell membranes. It has been primarily used in the treatment of life-threatening infections caused by multidrug-resistant Gram-negative bacteria, particularlyPseudomonas aeruginosa. The drug has a very narrow therapeutic ratio, with neurotoxicity and nephrotoxicity being the...Keywords
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