Efficacy of 101 antimicrobials and other agents on the development ofCryptosporidium parvum in vitro
- 1 January 1996
- journal article
- research article
- Published by Taylor & Francis in Pathogens and Global Health
- Vol. 90 (6) , 603-615
- https://doi.org/10.1080/00034983.1996.11813090
Abstract
An in-situ ELISA was used as a primary screen to test the effects of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro. Over 40 of the compounds displayed some form of anticryptosporidial activity, and dose-response curves were generated for 40 of these. The in-situ ELISA makes a highly effective primary, pharmaceutical screen for C. parvum, to be used prior to more detailed microscopical, toxicological or in-vivo assays.Keywords
This publication has 36 references indexed in Scilit:
- A rapid microcentrifuge procedure for purification of Cryptosporidium sporozoitesJournal of Microbiological Methods, 1996
- The activity of halofuginone in immunosuppressed rats infected with Cryptosporidium parvumJournal of Antimicrobial Chemotherapy, 1995
- Inhalation Therapy of Paromomycin Is Effective for Respiratory Infection and Hypoxia by Cryptosporidium With AIDSThe Lancet Healthy Longevity, 1995
- A Comparison Of Anticryptosporidial Activity Of Paromomycin With That Of Other Aminoglycosides And Azithromycin In Immunosuppressed RatsThe Journal of Infectious Diseases, 1994
- Paromomycin for Cryptosporidiosis in AIDS: A Prospective, Double-Blind TrialThe Journal of Infectious Diseases, 1994
- A simple and reliable method of producing in vitro infections ofcryptosporidium parvum(apicomplexa)FEMS Microbiology Letters, 1994
- Anticryptosporidial Activity of Lasalocid and Other Ionophorous Antibiotics in Immunosuppressed RatsThe Journal of Infectious Diseases, 1993
- Azithromycin for treatment of severe Cryptosporidium diarrhea in two children with cancerThe Journal of Pediatrics, 1993
- Clarithromycin-Minocycline is Synergistic in a Murine Model of ToxoplasmosisThe Journal of Infectious Diseases, 1992
- Optimization of the tetrazolium-based colorimetric assay for the measurement of cell number and cytotoxicityInternational Journal of Immunopharmacology, 1988