A Case of Relapsing Polychondritis Associated with Aortic Insufficiency

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Abstract
Clinical characteristics of this disease were systemic inflammatory involvement of cartilages, often complicated with conjunctivitis, scleritis, iritis, otitis interna and otitis media. Acute exacerbation and spontaneous remission of systemic chondritis were characteristic. The etiology was still obscure, but according to Pearson, an unusual hypersensitive direct reaction to cartilage, sclera and membranes of the middle and internal ear, and some specific acquired deficiency of metabolism or harmful enzyme may be the important factors. Speculation on etiological relation between relapsing polychondritis and aortic insufficiency was made. Corticosteroid therapy was effective in controlling the acute exacerbation.

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