Mechanical Property Changes of Barium Titanate (Ceramic) After in Vivo and in Vitro Aging
- 1 January 1977
- journal article
- research article
- Published by Taylor & Francis in Biomaterials, Medical Devices, and Artificial Organs
- Vol. 5 (3) , 267-276
- https://doi.org/10.3109/10731197709118677
Abstract
Since barium titanate (BaTi03) can be made piezoelectric, it may be used to substitute hard tissues directly. As a first step in testing this concept, a series of in vivo and in vitro aging and biocompatibility studies were performed. The mean compressive strength of samples implanted subcutaneously in the backs of rabbits decreased to 138 MPa after 20 weeks from a control value of 281 MPa. Similar, though less drastic losses of strength were seen when specimens were aged in distilled water (182 MPa at 28 weeks) and Ringer's solution (159 MPa at 28 weeks). The most rapid decrease of strength in all cases was seen prior to 4 weeks. Thereafter, the decrease was much slower. Histological evaluation of the tissue surrounding the implant revealed a thin fibrous capsule and no evidence of tissue inflammation.This publication has 4 references indexed in Scilit:
- Biomaterials—The Interfacial ProblemPublished by Elsevier ,1975
- The in vitro aging of porous Al2O3Journal of Biomedical Materials Research, 1973
- Attachment of bone to threaded implants by ingrowth and mechanical interlockingJournal of Biomedical Materials Research, 1972
- Piezoelectric Effect in BoneNature, 1963