CLASSIFICATION OF THE HEMATOLOGIC VARIATIONS AND ABNORMALITIES ASSOCIATED WITH BOECK’S SARCOID; REVIEW OF THE LITERATURE

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Abstract
The hematologic aspects of Boeck’s sarcoid are reviewed. Anemia is uncommon. The leukocyte count and differential picture are variable; they may be normal, or leukopenia may exist; leukocytosis is less commonly found. Eosinophilia may be present, and the monocytes may be increased. Abnormalities such as secondary polycythemia and leukemoid reaction are rare but may be causally related. Major disturbances include hemolytic anemia and thrombocytopenic purpura. The causal relationships between Boeck’s sarcoid and hemolytic anemia and thrombocytopenic purpura, although suggestive, have not been definitely established. A case of sarcoidosis with splenomegaly and thrombocytopenic purpura with recovery of the thrombocytopenia following splenectomy is reported and discussed.