Disseminated Herpes Simplex (Kaposi's Varicelliform Eruption) and the Failure of Penicillin and Aureomycin to Influence Its Course
- 3 May 1951
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 244 (18) , 670-672
- https://doi.org/10.1056/nejm195105032441804
Abstract
KRAPOSI'S varicelliform eruption is now known to be a clinical syndrome characterized by a virus infection superimposed on a chronic dermatitis, usually an atopic eczema. The responsible virus is either the herpes-simplex virus or the vaccinia virus. When the etiologic agent is known, the disease is more aptly called "disseminated herpes simplex" or "generalized vaccinia."In the past, these two virus infections of the skin could usually be differentiated only by specialized laboratory procedures, or by the microscopical demonstration in biopsies of early vesicles of the inclusion bodies characteristic of herpes simplex (Lipschütz bodies) or of vaccinia (Guarnieri bodies).1 , 2 , 3 Tzanck . . .Keywords
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