Definition of mean residence times in pharmacokinetics
- 1 January 1987
- journal article
- research article
- Published by Wiley in Biopharmaceutics & Drug Disposition
- Vol. 8 (1) , 87-97
- https://doi.org/10.1002/bdd.2510080110
Abstract
A new definition of the mean residence time is proposed which includes the commonly used definition as a special case. The advantage of the new definition is that it applies for both linear and non-linear systems. Some practical advantages which follow from the new definition are discussed. Procedures for using urinary excretion data in mean residence time estimation are discussed.Keywords
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