Lymphocyte Subsets in HLA‐DR2‐Positive Narcoleptic Patients

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Abstract
On the basis of our recent finding that all narcoleptic patients were HLA‐DR2 positive, peripheral blood lymphocyte subsets were examined in 30 HLA‐DR2 positive narcoleptic patients by using monoclonal antibodies and a flow cytometry. The percentages of OKIa1+ cells and OKM1+ cells increased significantly, while no quantitative changes were observed in the T cell subsets examined in the present study. No major immunological abnormalities which altered the T cell subpopulations quantitatively were apparent in narcolepsy.