Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease
Open Access
- 30 March 2009
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 23 (8) , 2459-2466
- https://doi.org/10.1096/fj.09-132928
Abstract
In Alzheimer's disease (AD), oxidative stress is present early and contributes to disease pathogenesis. We previously reported that in Tg19959 transgenic AD mice, partial deficiency of the mitochondr...Keywords
Funding Information
- National Institutes of Health (AG20729)
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