Production of antibacterial activities by two Bacillariophyceae grown in dialysis culture

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Abstract
Using a dialysis culture system for marine algae which allows for the recovery of high cell yield, an active component which inhibited gram-negative bacteria was detected in the aqueous phase of the algal extracts. Results show a direct relation between cell growth phase at time of harvest and the activity observed. It was possible to confirm previous results whereby Bacillariophyceae were shown to produce lipophilic substances inhibiting gram-positive terrestrial and marine bacteria. Apparently, Skeletonema costatum is more active than Phaeodactylum tricornutum against staphyloccoci.