Treatment of Generalized Pustular Psoriasis with Ro-10-9359

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Abstract
4 patients suffering from generalized pustular psoriasis, von Zumbusch type, were treated with the aromatic retinoid Ro-10-9359. Lesions were completely cleared after 4 weeks of therapy. A maintenance dose was usually required to prevent relapses. Side-effects were often observed but always remained very mild. Ro-10-9359 represents the best available treatment for generalized pustular psoriasis.