Naloxone and morphine inhibit gastric emptying of solids
- 1 May 1982
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology
- Vol. 60 (5) , 732-734
- https://doi.org/10.1139/y82-100
Abstract
Gastric emptying studies were performed on six healthy volunteers using a radioisotope test meal. Each subject was studied three times (control, morphine 7.5 mg, naloxone 2 mg). Both intravenous morphine and intravenous naloxone significantly delayed gastric emptying when compared with the control study. These results suggest that opiate receptors, opiate neurones, and enkephalin may regulate gastric motility and that under certain circumstances naloxone may act as an opiate agonist.This publication has 8 references indexed in Scilit:
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