Allergy to Viral and Rickettsial Vaccines

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Abstract
THE problem of the possible acquisition of hypersensitivity to egg protein from repeated injection of vaccine derived from viruses or rickettsiae and propagated on chick embryo is a subject of current interest. An editorial comment1 on an article published by us2 raised this question and maintained that it is a possibility that must be seriously entertained, as follows: "The immunity following the injection of influenza vaccines is short-lived, and reinjections at least every two or three years and perhaps again at the first evidence of an outbreak seem to be the only long range method of effective control with the . . .