Hypergammaglobulinemia in Experimental Liver Injury

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Abstract
The isolated perfused cirrhotic rat liver which is the site of mesenchymal cell proliferation incorporates 3 times as much C14 lysine into serum gamma globulin as the normal liver from litter mate controls. Hypergammaglobulinemia in active cirrhosis results partly from persistent increase of gamma globulin producing mesenchymal cells in the liver.