Protection against Brucella abortus in mice with O-polysaccharide-specific monoclonal antibodies
- 1 March 1986
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 51 (3) , 961-963
- https://doi.org/10.1128/iai.51.3.961-963.1986
Abstract
Mice injected with either of two monoclonal antibodies specific for the O polysaccharide of Brucella abortus prior to challenge infection had viable counts in spleens and livers significantly below those in control groups 1 and 4 weeks later. Two monoclonal antibodies specific for the porin of B. abortus failed to confer protection.This publication has 25 references indexed in Scilit:
- Immunochemical studies on the binding properties of Brucella abortus lipopolysaccharides to bovine precipitating antibodiesMolecular Immunology, 1984
- Immunity to Infection with Salmonella typhimurium: Mouse-Strain Differences in Vaccine- and Serum-Mediated ProtectionThe Journal of Infectious Diseases, 1984
- Monoclonal antibodies to Salmonella lipopolysaccharide: anti-O-polysaccharide antibodies protect C3H mice against challenge with virulent Salmonella typhimurium.The Journal of Immunology, 1984
- Pathogenesis and cellular immunity in experimental murine brucellosis.1984
- Derivation of monoclonal antibodies against antigensVeterinary Immunology and Immunopathology, 1983
- In vivo and in vitro effects of monoclonal antibody to Ly antigens on immunity to infectionCellular Immunology, 1982
- IMMUNOPROTECTION OF RATS AGAINST HAEMOPHILUS INFLUENZAE TYPE B DISEASE MEDIATED BY MONOCLONAL ANTIBODY AGAINST A HAEMOPHILUS OUTER-MEMBRANE PROTEINThe Lancet, 1982
- THE IMMUNOLOGICAL BASIS OF ACQUIRED CELLULAR RESISTANCEThe Journal of Experimental Medicine, 1964
- Passive Protection Experiments with Brucella AntiseraEpidemiology and Infection, 1955
- Studies in the Pathology and Pathogenesis of Experimental Brucellosis: II. The Formation of the Hepatic Granuloma and its EvolutionThe Journal of Infectious Diseases, 1951