Incubation Conditions and Reversibility of a New Non‐Depolarizing Neurornuscular Blocking Agent, Org‐NC45
- 1 October 1980
- journal article
- Published by Wiley in Acta Anaesthesiologica Scandinavica
- Vol. 24 (5) , 423-425
- https://doi.org/10.1111/j.1399-6576.1980.tb01576.x
Abstract
We describe the clinical use, for intubation purposes, of Org-NC45, a new non-depolarizing neuromuscular blocking agent. Administration of 50 and 72 microgram/kg of this drug allowed good to excellent endotracheal intubation conditions within 3 and 2 min, respectively. In none of the cases ws a significant change in blood pressure or heart rate seen after the injection of Org-NC45. The resulting block was of short duration and, if necessary, was easily reversed with neostigmine or pyridostigmine.Keywords
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