MODULATION OF TRANSFERRIN RECEPTORS BY IRON, HEMIN AND PROTOPORPHYRIN .9.
- 1 January 1983
- journal article
- research article
- Vol. 297 (6) , 291-294
Abstract
The expression of transferrin [Trf] receptors in human leukemic cell lines was investigated. Heme, Fe and protoporphyrin-IX may modulate the expression of Trf receptors: Fe and heme induce a decrease in the number of Trf receptors; in contrast protoporphyin-IX elicited a significant increase in the number of Trf receptors. The intracellular concentration of Fe, heme and protoporphyrin-IX may represent the main factor involved in the regulation of the expression of Trf receptors.This publication has 11 references indexed in Scilit:
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