X-RAY MICROPROBE ANALYSIS OF MICHAELIS-GUTMANN BODIES IN HUMAN AND EXPERIMENTAL MALAKOPLAKIA

  • 1 January 1978
    • journal article
    • research article
    • Vol. 90  (2) , 411-+
Abstract
Using X-ray microprobe analysis, Michaelis-Gutmann bodies (M-G bodies) were studied in malakoplakia tissue samples from human kidney and testis as well as from lesions experimentally induced in the rat. In all the M-G bodies tested Ca was detected at both its K.alpha. and K.beta. lines. The actual amount of Ca depended on the developmental stage, i.e., on the degree of calcification of the M-G body. In M-G bodies of rat kidney malakoplakia tissue fixed without osmium tetroxide, P could also be detected unambiguously. The ratios of Ca and P percentages wt/wt indicated that CaHPO4 was present. No difference was found between M-G bodies in malakoplakia tissues of human origin and those in experimentally induced malakoplakia.