Chromosomal localization of human gene for histidyl-tRNA synthetase: Clustering of genes encoding aminoacyl-tRNA synthetases on human chromosome 5
- 1 September 1986
- journal article
- conference paper
- Published by Springer Nature in Somatic Cell and Molecular Genetics
- Vol. 12 (5) , 513-517
- https://doi.org/10.1007/bf01539922
Abstract
The gene encoding histidyl-tRNA synthetase was localized to human chromosome 5 using human-Chinese hamster ovary cell hybrids. Seven of the functionally related genes encoding the 20 different aminoacyl-tRNA synthetases have now been mapped in humans and four are located on a single chromosome, number 5, which represents less than 7 % of the total genome. Thus, there appears to be significant clustering of this group of genes which may reflect their evolutionary relatedness or common factors involved in regulating their expression.This publication has 11 references indexed in Scilit:
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