Abstract
According to several recent reports,1 , 2 including that of Weiss et al. in this issue of the Journal,3 it now seems that there are not two, but three classes of bilirubin: free, conjugated, and covalently bound. The younger reader's eyes may glaze at the thought of yet another obscure article on bilirubin metabolism. The new distinction, however, is worth considering in the light of the old one between "directly reacting" and "indirectly reacting" bilirubin.It will be recalled that during the first half of this century, a small group of physicians brought to the study of bilirubin metabolism the same . . .