Search for mutations affecting protein structure in children of atomic bomb survivors: preliminary report.
- 1 July 1980
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 77 (7) , 4221-4225
- https://doi.org/10.1073/pnas.77.7.4221
Abstract
A total of 289,868 locus tests, based on 28 different protein phenotypes and using one-dimensional electrophoresis to detect variant proteins, has yielded one probable mutation in the offspring of "proximally exposed" parents, who received an estimated average gonadal exposure of 31 to 39 rem in the atomic bombings of Hiroshima and Nagasaki. There were no mutations in 208,196 locus tests involving children of "distally exposed" parents, who had essentially no radiation exposure.Keywords
This publication has 19 references indexed in Scilit:
- FREQUENCY OF PRIVATE ELECTROPHORETIC VARIANTS IN AUSTRALIAN ABORIGINES AND INDIRECT ESTIMATES OF MUTATION-RATE1979
- Dose-response relationship of neutron and gamma rays to chromosomally aberrant cells among atomic bomb survivors in Hiroshima and Nagasaki.Journal of Radiation Research, 1979
- The frequency in Japanese of genetic variants of 22 proteins: IV. Acid phosphatase, NADP-isocitrate dehydrogenase, peptidase A, peptidase B and phosphohexose isomeraseAnnals of Human Genetics, 1978
- The frequency in Japanese of genetic variants of 22 proteins III. Phosphoglucomutase-1, phosphoglucomutase-2, 6-phosphogluconate dehydrogenase, adenylate kinase, and adenosine deaminaseAnnals of Human Genetics, 1977
- The frequency in Japanese of genetic variants of 22 proteinsAnnals of Human Genetics, 1977
- Spontaneous mutation rates at enzyme loci in Drosophila melanogaster.Proceedings of the National Academy of Sciences, 1977
- B. Genetic Effects 2. Cytogenetic StudyJournal of Radiation Research, 1975
- B. Physical Dose Estimates for A-bomb Survivors —Studies at Chiba, JapanJournal of Radiation Research, 1975
- SOME FURTHER OBSERVATIONS ON SEX RATIO AMONG INFANTS BORN TO SURVIVORS OF ATOMIC BOMBINGS OF HIROSHIMA AND NAGASAKI1966
- A COHORT-TYPE STUDY OF SURVIVAL IN CHILDREN OF PARENTS EXPOSED TO ATOMIC BOMBINGS1966