The frequency in Japanese of genetic variants of 22 proteins III. Phosphoglucomutase-1, phosphoglucomutase-2, 6-phosphogluconate dehydrogenase, adenylate kinase, and adenosine deaminase

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Abstract
Five enzyme systems, PGM1, PGM2, ADA, 6‐PGD and AK, were examined by electrophoresis in over 4000 samples from Hiroshima and Nagasaki for the frequencies of common and rare variants. In the PGM1, system, the PGM21 allele and PGM71; allele were found in polymorphic proportions. I n addition, five kinds of slow variants and three types of fast variants of PGM1 were detected. The PGM3 NGS 11 allele was found in five individuals from Nagasaki, but was not observed in samples from Hiroshima. There were no variants of PGM2. Three kinds of fast variants of 6‐PGD were detected. NO variation in AK was observed. There were no rare variants of ADA. The 6‐PGDc allele had a frequency of 0.084 in Hiroshima, and 0.093 in Nagasaki, and the ADA2 allele frequencies of 0.025 in Hiroshima and 0.032 in Nagasaki.