DUODENAL SOMATOSTATINOMA Immunohistopathology and Review of Literature

Publisher Website
Google Scholar
Abstract
A case of duodenal somatostatinoma is reported. The patient, a 54 yr old male, had complained of an epigastric pain due to gastric ulcer and a duodenal polyp was unexpectedly found at a gastrectomy. The polyp showed basically tubular adenocarcinoma, with negative argyrophil and argentaffin reactions. By an indirect immunofluorescent examination almost all of the tumor cells were revealed as somatostatin-immunoreactive. Big somatostatin was also positive. Radioimmunoassay of the tumor indicated 6400 pg somatostatin-like immunoreactivity/mg wet tissue. This appears to be the 2nd case of duodenal somatostatinoma.