GLUCOSE‐6‐PHOSPHATE DEHYDROGENASE ACTIVITY IN HUMAN BREAST CANCER
- 1 March 1981
- journal article
- research article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Section A Pathology
- Vol. 89A (1-6) , 263-270
- https://doi.org/10.1111/j.1699-0463.1981.tb00220.x
Abstract
The correlation between glucose-6-phosphate dehydrogenase activity and different tumour characteristics was investigated in human breast cancer tissue. The enzyme activity was measured by a histochemical method and the oestrogen receptor content by a dextran-coated charcoal assay. The proliferative activity of the tumours correlated positively with the glucose-6-phosphate dehydrogenase activity. No correlation was found between enzyme activity and tumour type and menopausal status, age, TNM-class nor oestrogen receptor content. Based on this investigation it is concluded that the activity of glucose-6-phosphate dehydrogenase reflects the proliferative status of the tumour but not the hormone dependency of the tumour.Keywords
This publication has 14 references indexed in Scilit:
- Oestrogen-receptor determinations on fine-needle aspirations from malignant tumours of the breastPublished by Elsevier ,1979
- Reproducibility of measurements of oestrogen-receptor concentration in breast cancerBritish Journal of Cancer, 1977
- Current status of estrogen and progesterone receptors in breast cancerCancer, 1977
- Estradiol receptors and glucose-6-phosphate dehydrogenase activity in human breast tumorsClinica Chimica Acta; International Journal of Clinical Chemistry, 1977
- Multiple molecular forms of lactate dehydrogenase and glucose 6-phosphate dehydrogenase in normal and abnormal human breast tissuesCancer, 1976
- The activity of mitochondrial α-glycerophosphate dehydrogenase in the rat nephron following triiodo-L-Thyronine treatmentHistochemistry and Cell Biology, 1976
- Enzyme patterns of glucose catabolism in hormone-dependent and -independent mammary tumours of GR micePublished by Elsevier ,1973
- Further enzyme histochemical observations on the segmentation of the proximal tubules in the kidney of the male ratHistochemistry and Cell Biology, 1973
- Quantitative Dehydrogenase Histochemistry with special Reference to the Pentose Shunt DehydrogenasesProgress in Histochemistry and Cytochemistry, 1972
- FIBRO-ADENOMATOSIS AND BREAST CARCINOMAActa Pathologica Microbiologica Scandinavica Section A Pathology, 1970