Investigations on vitamine E and lipid peroxide status in rheumatic diseases

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Abstract
Summary Patients of both sexes suffering from two types of rheumatic diseases — rheumatoid arthritis and osteoarthrosis — were examined. Healthy volunteers of similar age served as controls. No significant difference was found in the plasma vitamin E content of the patients. Plasma malondialdehyde content was significantly higher/P< 0.001/in both sexes in the RA and OA groups as compared to the controls. Plasma catalase activity in both sexes was significantly higher (P<0.01) in RA and OA groups while RBC glutathione-peroxidase showed significantly (P<0.001) higher activity only in the female RA group, as compared to the control subjects. A difference was found between RA and OA groups in malondialdehyde content and in glutathione-peroxidase activity in subjects of both sexes.