Inherited Deficiency of Antithrombin III in Two Italian Families
- 1 January 1982
- journal article
- research article
- Published by S. Karger AG in Pathophysiology of Haemostasis and Thrombosis
- Vol. 12 (3) , 300-308
- https://doi.org/10.1159/000214687
Abstract
A significant decrease of plasma antithrombin III (AT III) levels, measured with four different biological and immunological methods, was found in 8 of 11 members of a Sicilian family (family DM) and in 3 of 14 members of a northern Italian family (family A). Different behaviour after oral anticoagulant treatment with acenocoumarin was seen in 2 long-term treated subjects. The propositus of family DM, who had had a long history of recurrent thrombosis, did not show any increase of AT III levels. A significant increase was, on the contrary, observed in the propositus of family A, who had suffered a recent thrombosis in a branch of the inferior mesenteric vein.This publication has 3 references indexed in Scilit:
- Inherited deficiency of antithrombin III in an Italian kindredLa Ricerca in Clinica e in Laboratorio, 1980
- Some Immunological Investigations on Antithrombin III ‘Budapest’British Journal of Haematology, 1978
- Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodiesAnalytical Biochemistry, 1966