Luteinizing Hormone-Releasing Hormone Downstaging of Clinical Stage C Prostate Cancer
- 1 March 1992
- journal article
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 147 (3 Part 2) , 891-893
- https://doi.org/10.1016/s0022-5347(17)37414-1
Abstract
A total of 7 patients with clinical stage C prostate cancer determined by digital rectal examination, transrectal ultrasonography, radionuclide bone scanning and serum prostatic acid phosphatase determination was treated with luteinizing hormone-releasing hormone analogues for 2 to 5 months in an attempt to downstage the disease. Although substantial decreases in prostate specific antigen level and prostatic volume occurred, only 2 patients experienced pathological downstaging of disease. We conclude that luteinizing hormone-releasing hormone therapy for downstaging of clinical stage C prostatic cancer is of limited value.Keywords
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