The Effect of Reserpine on Adrenal Medulla of the Pigeon-a Cytochemical Investigation

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Abstract
In the present report the localization and concentration of cytochemically demonstrable adrenaline and noradrenaline in the suprarenal medulla or normal and reserpine treated pigeons is described. Even a minute dose (.05 mg/100 gm b. wt.) of reserpine can cause an almost total depletion of noradrenaline. There is also a loss of adrenaline from the core of individual cords. It is interesting to note that considerably high dosages (.08 mg-1.70 mg) or reserpine does not cause depletion of adrenaline from the peripheral zone of the chromaffin cords. The differential response of adrenaline and noradrenaline to reserpine in the pigeon suprarenal medulla is discussed in the light of current researches.

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